Plasma cell , multiple myelome

The principal methods employed in hematological diagnosis

Orthochromatic normoblast

Cabot ring and Normoblast

54 year old female WBC 14.2 RBC 2.79 HGB 8.6 PLT 122 Numerous NRBC’s. (80 counted) CML with a large quantity of micromegakaryocytes (cells – 4A, B, C, D; 5A, B, C, D; 6A, B, C, D)

Diagnosed with Mantle Cell Lymphoma. The condition is an uncommon type of non-Hodgkin’s lymphoma that mostly affects older adults

ALL L3 burkitt lymphoma

Trypanosoma Gambiensis

Grey platelet syndrome (GPS) is a rare, congenital disorder which causes a bleeding disorder. The platelets are large and have a grey appearance on light microscopy. It is one of the macrothrombocytopenias, which are inherited thrombocytopenias with increased platelet size

Platelet morphology

Chédiak-Higashi syndrome. The granulocytes contain huge cytoplasmic granules formed from aggregation and fusion of azurophilic and specific granules. Large abnormal granules are found in other granule-containing cells throughout the body

Chronic myelomonocytic leukemia Dysplastic monocytes and Promonocytes

Morphology of small lymphoid cell neoplasms

Examples of lymphoid cell neoplasms of intermediate and large cell size

Plasmodium falciparum Gametocytes

Neutrophilic Cells. The images shows myelocyte (1), band neutrophils (2), two lobed neutrophil (3) and neutrophils (4)

neutrophilic myeloid precursors

There is a basophil in the center of the field which has a lobed nucleus (like PMN's) and numerous coarse, dark blue granules in the cytoplasm. They are infrequent in a normal peripheral blood smear, and their significance is uncertain. A band neutrophil is seen on the left, and a large, activated lymphocyte on the right.

Neutrophils (neutrophilic granulocytes)

Plasmodium falciparum

Plasmodium vivax

Neutrophil Alphabets

plasmodium

Beta-Thalassemia

mature lymphocytes they are indicative of chronic lymphocytic leukemia, a disease most often seen in older adults

T cell leukemia

hairy cell leukemia

giant platelet

LLA-L3 acute lymphoblastic leukemia

Juvenile myelomonocytic leukaemia

Acute myeloid leukaemia showing leukaemic blast cells, several with Auer rods

reticulocytosis

One sickle cell and several boat-shaped cells (in sickle cell anaemia)

Hereditary spherocytosis (HS)

Hereditary elliptocytosis (HE)

Howell Jolly body

Target cells

Eosynophilia

1 reactive lymphocytes 2 Polychromatic erythrocyte

Erythropoiesis

Granulopoiesis

a-band form of neutrophil, b-monocyte,c-lymphocyte,d-eosinophil. e-neutrophil,f-basophil,g-rbc

Monocyte, with a band neuthrophil at upper left

Monocyte with phagocytized nuclear residue

Plasma cell from peripheral blood (“blood plasma cell”) with highly basophilic cytoplasm and a perinuclear halo

Two basophils

Two blasts mieloblastos

Red blood cell and platelet interactions in healthy females during early and late pregnancy

Increased granulocytopoiesis in a bone marrow smear. Neutrophilic granulocytes,two basophils, and four eosinophils medula ossea

Hairy cells Leukemia The neoplastic cells express CD20, CD19, CD11c, CD25, and CD103 in typical cases